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Aminopurvalanol A, a Potent, Selective, and Cell Permeable Inhibitor of Cyclins/Cdk Complexes, Causes the Reduction of in Vitro Fertilizing Ability of Boar Spermatozoa, by Negatively Affecting the Capacitation-Dependent Actin Polymerization

The adoption of high-througput technologies demonstrated that in mature spermatozoa are present proteins that are thought to be not present or active in sperm cells, such as those involved in control of cell cycle. Here, by using an in silico approach based on the application of networks theory, we...

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Bibliografiske detaljer
Udgivet i:Front Physiol
Main Authors: Bernabò, Nicola, Valbonetti, Luca, Greco, Luana, Capacchietti, Giulia, Ramal Sanchez, Marina, Palestini, Paola, Botto, Laura, Mattioli, Mauro, Barboni, Barbara
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744433/
https://ncbi.nlm.nih.gov/pubmed/29312003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.01097
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