Aminopurvalanol A, a Potent, Selective, and Cell Permeable Inhibitor of Cyclins/Cdk Complexes, Causes the Reduction of in Vitro Fertilizing Ability of Boar Spermatozoa, by Negatively Affecting the Capacitation-Dependent Actin Polymerization

The adoption of high-througput technologies demonstrated that in mature spermatozoa are present proteins that are thought to be not present or active in sperm cells, such as those involved in control of cell cycle. Here, by using an in silico approach based on the application of networks theory, we...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Bernabò, Nicola, Valbonetti, Luca, Greco, Luana, Capacchietti, Giulia, Ramal Sanchez, Marina, Palestini, Paola, Botto, Laura, Mattioli, Mauro, Barboni, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744433/
https://ncbi.nlm.nih.gov/pubmed/29312003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2017.01097
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