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Retinoblastoma
Retinoblastoma is a rare cancer of the infant retina, which forms when both RB1 alleles mutate in a susceptible retinal cell, likely a cone photoreceptor precursor. Loss of the tumour suppressor functions of the retinoblastoma protein, pRB, leads to uncontrolled cell division and recurrent genomic c...
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| Publicado en: | Nat Rev Dis Primers |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5744255/ https://ncbi.nlm.nih.gov/pubmed/27189421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrdp.2015.21 |
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