Retinoblastoma

Retinoblastoma is a rare cancer of the infant retina, which forms when both RB1 alleles mutate in a susceptible retinal cell, likely a cone photoreceptor precursor. Loss of the tumour suppressor functions of the retinoblastoma protein, pRB, leads to uncontrolled cell division and recurrent genomic c...

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Bibliografiske detaljer
Udgivet i:Nat Rev Dis Primers
Main Authors: Dimaras, Helen, Corson, Timothy W., Cobrinik, David, White, Abby, Zhao, Junyang, Munier, Francis L., Abramson, David H., Shields, Carol L., Chantada, Guillermo L., Njuguna, Festus, Gallie, Brenda L.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744255/
https://ncbi.nlm.nih.gov/pubmed/27189421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrdp.2015.21
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