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Systems Pharmacology of VEGF165b in Peripheral Artery Disease

We built a whole‐body computational model to study the role of the poorly understood vascular endothelial growth factor (VEGF)(165b) splice isoform in peripheral artery disease (PAD). This model was built and validated using published and new experimental data from cells, mice, and humans, and expli...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Clegg, Lindsay E., Ganta, Vijay C., Annex, Brian H., Mac Gabhann, Feilim
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744173/
https://ncbi.nlm.nih.gov/pubmed/29193887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12261
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