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Systems Pharmacology of VEGF165b in Peripheral Artery Disease

We built a whole‐body computational model to study the role of the poorly understood vascular endothelial growth factor (VEGF)(165b) splice isoform in peripheral artery disease (PAD). This model was built and validated using published and new experimental data from cells, mice, and humans, and expli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:CPT Pharmacometrics Syst Pharmacol
Hauptverfasser: Clegg, Lindsay E., Ganta, Vijay C., Annex, Brian H., Mac Gabhann, Feilim
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5744173/
https://ncbi.nlm.nih.gov/pubmed/29193887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12261
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