Dual radiosensitization and anti-STAT3 anti-proliferative strategy based on delivery of gold nanoparticle - oligonucleotide nanoconstructs to head and neck cancer cells.

Constitutively activated signal transducer and activator of transcription 3 (STAT3) factor is an important therapeutic target in head and neck cancer (HNC). Despite early promising results, a reliable systemic delivery system for STAT3- targeted oligonucleotide (ODN) drugs is still needed for future...

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Bibliographic Details
Published in:Nanotheranostics
Main Authors: Zhang, Surong, Gupta, Suresh, Fitzgerald, Thomas J, Bogdanov, Alexei A
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2018
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743834/
https://ncbi.nlm.nih.gov/pubmed/29291159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/ntno.22335
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