circRNA Mediates Silica-Induced Macrophage Activation Via HECTD1/ZC3H12A-Dependent Ubiquitination

Rationale: Phagocytosis of silicon dioxide (SiO(2)) into lung cells causes an inflammatory cascade that results in fibroblast proliferation and migration, followed by fibrosis. Circular RNAs (circRNAs) are a subclass of non-coding RNAs detected within mammalian cells; however, researchers have not d...

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Detalles Bibliográficos
Publicado en:Theranostics
Main Authors: Zhou, Zewei, Jiang, Rong, Yang, Xiyue, Guo, Huifang, Fang, Shencun, Zhang, Yingming, Cheng, Yusi, Wang, Jing, Yao, Honghong, Chao, Jie
Formato: Artigo
Idioma:Inglês
Publicado: Ivyspring International Publisher 2018
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743568/
https://ncbi.nlm.nih.gov/pubmed/29290828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.21648
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