Dual Targeting of Acute Leukemia and Supporting Niche by CXCR4-Directed Theranostics

C-X-C chemokine receptor 4 (CXCR4) is a transmembrane receptor with pivotal roles in cell homing and hematopoiesis. CXCR4 is also involved in survival, proliferation and dissemination of cancer, including acute lymphoblastic and myeloid leukemia (ALL, AML). Relapsed/refractory ALL and AML are freque...

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Bibliographic Details
Published in:Theranostics
Main Authors: Habringer, Stefan, Lapa, Constantin, Herhaus, Peter, Schottelius, Margret, Istvanffy, Rouzanna, Steiger, Katja, Slotta-Huspenina, Julia, Schirbel, Andreas, Hänscheid, Heribert, Kircher, Stefan, Buck, Andreas K., Götze, Katharina, Vick, Binje, Jeremias, Irmela, Schwaiger, Markus, Peschel, Christian, Oostendorp, Robert, Wester, Hans-Jürgen, Grigoleit, Götz-Ulrich, Keller, Ulrich
Format: Artigo
Language:Inglês
Published: Ivyspring International Publisher 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743554/
https://ncbi.nlm.nih.gov/pubmed/29290814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.21397
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