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Acid-degradable Dextran as an Image Guided siRNA Carrier for COX-2 Downregulation

Purpose: Effective in vivo delivery of siRNA to silence genes is a highly sought-after goal in the treatment of multiple diseases. Cyclooxygenase-2 (COX-2) is a major mediator of inflammation and its effective and specific downregulation has been of major interest to treat conditions ranging from au...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Chen, Zhihang, Krishnamachary, Balaji, Penet, Marie-France, Bhujwalla, Zaver M.
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743456/
https://ncbi.nlm.nih.gov/pubmed/29290789
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.21052
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