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Nanoplex delivery of siRNA and Prodrug Enzyme for Multimodality Image-Guided Molecular Pathway Targeted Cancer Therapy

The ability to destroy cancer cells while sparing normal tissue is highly sought after in cancer therapy. Small interfering RNA (siRNA)-mediated silencing of cancer-cell specific targets, or the use of a prodrug enzyme delivered to the tumor to convert a non-toxic prodrug to an active drug are two p...

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Detalhes bibliográficos
Main Authors: Li, Cong, Penet, Marie-France, Wildes, Flonné, Takagi, Tomoyo, Chen, Zhihang, Winnard, Paul T., Artemov, Dmitri, Bhujwalla, Zaver M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991391/
https://ncbi.nlm.nih.gov/pubmed/20958072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn102187v
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