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eIF2α Phosphorylation Mediates IL24-induced Apoptosis through Inhibition of Translation

Interleukin 24 (IL24) is an immunomodulatory cytokine that also displays broad cancer-specific suppressor effects. The tumor suppressor activities of IL-24 include inhibition of angiogenesis, sensitization to chemotherapy, and cancer-specific apoptosis. Supra-physiologic activation and/or overexpres...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cancer Res
Prif Awduron: Persaud, Leah, Zhong, Xuelin, Alvarado, Giselle, Do, Winchie, Dejoie, Jordan, Zybtseva, Anna, Aktas, Bertal Huseyin, Sauane, Moira
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743333/
https://ncbi.nlm.nih.gov/pubmed/28461326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-16-0454
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