Tacrolimus nanoparticles based on chitosan combined with nicotinamide: enhancing percutaneous delivery and treatment efficacy for atopic dermatitis and reducing dose

BACKGROUND: Topical application of tacrolimus (FK506) was effective in the treatment of atopic dermatitis (AD); however, adverse effects frequently occurred with the increase of FK506 dose during long–term treatment. OBJECTIVE: The objective of this project was to develop a hybrid skin targeting sys...

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Bibliografski detalji
Izdano u:Int J Nanomedicine
Glavni autori: Yu, Kaiyue, Wang, Yixuan, Wan, Tao, Zhai, Yuanhao, Cao, Sisi, Ruan, Wenyi, Wu, Chuanbin, Xu, Yuehong
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2017
Teme:
Original Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5743175/
https://ncbi.nlm.nih.gov/pubmed/29317821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S150319
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