Combination of hydrotropic nicotinamide with nanoparticles for enhancing tacrolimus percutaneous delivery

Tacrolimus (FK506), an effective immunosuppressant for treating inflammatory skin diseases, hardly penetrates into and through the skin owing to its high hydrophobicity and molecular weight. The aim of this study was to develop a hybrid system based on nicotinamide (NIC) and nanoparticles (NPs) enca...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Pan, Wenhui, Qin, Mengyao, Zhang, Guoguang, Long, Yueming, Ruan, Wenyi, Pan, Jingtong, Wu, Zushuai, Wan, Tao, Wu, Chuanbin, Xu, Yuehong
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4998035/
https://ncbi.nlm.nih.gov/pubmed/27578973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S108545
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