Both Systemic and Intra-articular Immunization with Citrullinated Peptides Are Needed to Induce Arthritis in the Macaque

OBJECTIVES: Anti-citrullinated peptides antibodies (ACPAs) have high specificity for the diagnosis of rheumatoid arthritis (RA), but their role in the pathophysiology is not fully established. The main genetic risk factor for RA, the shared epitope in major histocompatibility complex class II, is as...

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書目詳細資料
發表在:Front Immunol
Main Authors: Bitoun, Samuel, Roques, Pierre, Larcher, Thibaut, Nocturne, Gaétane, Serguera, Che, Chrétien, Pascale, Serre, Guy, Grand, Roger Le, Mariette, Xavier
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
主題:
Immunology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742322/
https://ncbi.nlm.nih.gov/pubmed/29326703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.01816
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