Osteolytic Breast Cancer Causes Skeletal Muscle Weakness in an Immunocompetent Syngeneic Mouse Model

Muscle weakness and cachexia are significant paraneoplastic syndromes of many advanced cancers. Osteolytic bone metastases are common in advanced breast cancer and are a major contributor to decreased survival, performance, and quality of life for patients. Pathologic fracture caused by osteolytic c...

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Bibliographische Detailangaben
Veröffentlicht in:Front Endocrinol (Lausanne)
Hauptverfasser: Regan, Jenna N., Mikesell, Carter, Reiken, Steven, Xu, Haifang, Marks, Andrew R., Mohammad, Khalid S., Guise, Theresa A., Waning, David L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Endocrinology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742151/
https://ncbi.nlm.nih.gov/pubmed/29312148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00358
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