Osteolytic Breast Cancer Causes Skeletal Muscle Weakness in an Immunocompetent Syngeneic Mouse Model

Muscle weakness and cachexia are significant paraneoplastic syndromes of many advanced cancers. Osteolytic bone metastases are common in advanced breast cancer and are a major contributor to decreased survival, performance, and quality of life for patients. Pathologic fracture caused by osteolytic c...

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Publicado en:Front Endocrinol (Lausanne)
Autores principales: Regan, Jenna N., Mikesell, Carter, Reiken, Steven, Xu, Haifang, Marks, Andrew R., Mohammad, Khalid S., Guise, Theresa A., Waning, David L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2017
Materias:
Endocrinology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5742151/
https://ncbi.nlm.nih.gov/pubmed/29312148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fendo.2017.00358
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