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Alternative dominance of the parental genomes in hybrid cells generated through the fusion of mouse embryonic stem cells with fibroblasts

For the first time, two types of hybrid cells with embryonic stem (ES) cell-like and fibroblast-like phenotypes were produced through the fusion of mouse ES cells with fibroblasts. Transcriptome analysis of 2,848 genes differentially expressed in the parental cells demonstrated that 34–43% of these...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Matveeva, Natalia M., Fishman, Veniamin S., Zakharova, Irina S., Shevchenko, Alexander I., Pristyazhnyuk, Inna E., Menzorov, Aleksei G., Serov, Oleg L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741742/
https://ncbi.nlm.nih.gov/pubmed/29273752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18352-4
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