Alternative dominance of the parental genomes in hybrid cells generated through the fusion of mouse embryonic stem cells with fibroblasts

For the first time, two types of hybrid cells with embryonic stem (ES) cell-like and fibroblast-like phenotypes were produced through the fusion of mouse ES cells with fibroblasts. Transcriptome analysis of 2,848 genes differentially expressed in the parental cells demonstrated that 34–43% of these...

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Publicat a:Sci Rep
Autors principals: Matveeva, Natalia M., Fishman, Veniamin S., Zakharova, Irina S., Shevchenko, Alexander I., Pristyazhnyuk, Inna E., Menzorov, Aleksei G., Serov, Oleg L.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741742/
https://ncbi.nlm.nih.gov/pubmed/29273752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18352-4
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