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Cytogenetic analysis and Dlk1-Dio3 locus epigenetic status of mouse embryonic stem cells during early passages

Mouse embryonic stem (ES) cells are widely used in early development studies and for transgenic animal production; however, a stable karyotype is a prerequisite for their use. We derived 32 ES cell lines of outbred mice (129 × BALB (1B), C57BL × 1B, and DD × 1B F1 hybrids). Pluripotency was assessed...

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Detalhes bibliográficos
Publicado no:Cytotechnology
Main Authors: Menzorov, Aleksei, Pristyazhnyuk, Inna, Kizilova, Helen, Yunusova, Anastasia, Battulin, Nariman, Zhelezova, Antonina, Golubitsa, Aleftina, Serov, Oleg
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4698258/
https://ncbi.nlm.nih.gov/pubmed/24969018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-014-9751-y
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