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Pediatric glioblastoma cells inhibit neurogenesis and promote astrogenesis, phenotypic transformation and migration of human neural progenitor cells within cocultures

Neural progenitor cell (NPC) fate is influenced by a variety of biological cues elicited from the surrounding microenvironment and recent studies suggest their possible role in pediatric glioblastoma multiforme (GBM) development. Since a few GBM cells also display NPC characteristics, it is not clea...

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Detalhes bibliográficos
Publicado no:Exp Cell Res
Main Authors: Farrell, Kurt, Mahajan, Gautam, Srinivasan, Parthasarathy, Lee, Moo-Yeal, Kothapalli, Chandrasekhar R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741502/
https://ncbi.nlm.nih.gov/pubmed/29129566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2017.11.013
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