KLF4 Regulation of Ch25h and LXR Mitigates Atherosclerosis Susceptibility

BACKGROUND: Atherosclerosis is a multifaceted inflammatory disease involving cells in the vascular wall [e.g., endothelial cells (ECs)] as well as circulating and resident immunogenic cells (e.g., monocytes/macrophages). Acting as a ligand for liver X receptor (LXR), but an inhibitor of sterol regul...

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Udgivet i:Circulation
Main Authors: Li, Zhao, Martin, Marcy, Zhang, Jin, Huang, Hsi-Yuan, Bai, Liang, Zhang, Jiao, Kang, Jian, He, Ming, Li, Jie, Maurya, Mano R., Gupta, Shakti, Zhou, Guangjin, Sangwung, Panjamaporn, Xu, Yong-Jiang, Lei, Ting, Huang, Hsien-Da, Jain, Mohit, Jain, Mukesh K., Subramaniam, Shankar, Shyy, John Y-J.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5741092/
https://ncbi.nlm.nih.gov/pubmed/28794002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.117.027462
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