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Circadian control of bile acid synthesis by a KLF15-Fgf15 axis

Circadian control of nutrient availability is critical to efficiently meet the energetic demands of an organism. Production of bile acids (BAs), which facilitate digestion and absorption of nutrients, is a major regulator of this process. Here we identify a KLF15-Fgf15 signalling axis that regulates...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Han, Sean (Shuxin), Zhang, Rongli, Jain, Rajan, Shi, Hong, Zhang, Lilei, Zhou, Guangjin, Sangwung, Panjamaporn, Tugal, Derin, Atkins, G. Brandon, Prosdocimo, Domenick A., Lu, Yuan, Han, Xiaonan, Tso, Patrick, Liao, Xudong, Epstein, Jonathan A., Jain, Mukesh K.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457302/
https://ncbi.nlm.nih.gov/pubmed/26040986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8231
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