Selection strategy of phage-displayed immunogens based on an in vitro evaluation of the Th1 response of PBMCs and their potential use as a vaccine against Leishmania infantum infection

BACKGROUND: The development of a vaccine for the prevention of visceral leishmaniasis (VL) still represents a significant unmet medical need. A human vaccine can be found if one takes into consideration that many people living in endemic areas of disease are infected but do not develop active VL, in...

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Detalhes bibliográficos
Publicado no:Parasit Vectors
Main Authors: Ramos, Fernanda Fonseca, Costa, Lourena Emanuele, Dias, Daniel Silva, Santos, Thaís Teodoro Oliveira, Rodrigues, Marcella Rezende, Lage, Daniela Pagliara, Salles, Beatriz Cristina Silveira, Martins, Vívian Tamietti, Ribeiro, Patrícia Aparecida Fernandes, Chávez-Fumagalli, Miguel Angel, Dias, Ana Carolina Silva, Alves, Patrícia Terra, Vieira, Érica Leandro Marciano, Roatt, Bruno Mendes, Menezes-Souza, Daniel, Duarte, Mariana Costa, Teixeira, Antonio Lúcio, Goulart, Luiz Ricardo, Coelho, Eduardo Antonio Ferraz
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740923/
https://ncbi.nlm.nih.gov/pubmed/29268793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13071-017-2576-8
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