Antigenicity, Immunogenicity and Protective Efficacy of Three Proteins Expressed in the Promastigote and Amastigote Stages of Leishmania infantum against Visceral Leishmaniasis

In the present study, two Leishmania infantum hypothetical proteins present in the amastigote stage, LiHyp1 and LiHyp6, were combined with a promastigote protein, IgE-dependent histamine-releasing factor (HRF); to compose a polyproteins vaccine to be evaluated against L. infantum infection. Also, th...

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Опубликовано в: :PLoS One
Главные авторы: Martins, Vivian Tamietti, Chávez-Fumagalli, Miguel Angel, Lage, Daniela Pagliara, Duarte, Mariana Costa, Garde, Esther, Costa, Lourena Emanuele, da Silva, Viviane Gomes, Oliveira, Jamil Silvano, de Magalhães-Soares, Danielle Ferreira, Teixeira, Santuza Maria Ribeiro, Fernandes, Ana Paula, Soto, Manuel, Tavares, Carlos Alberto Pereira, Coelho, Eduardo Antonio Ferraz
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2015
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569552/
https://ncbi.nlm.nih.gov/pubmed/26367128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137683
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