Antigenicity, Immunogenicity and Protective Efficacy of Three Proteins Expressed in the Promastigote and Amastigote Stages of Leishmania infantum against Visceral Leishmaniasis

In the present study, two Leishmania infantum hypothetical proteins present in the amastigote stage, LiHyp1 and LiHyp6, were combined with a promastigote protein, IgE-dependent histamine-releasing factor (HRF); to compose a polyproteins vaccine to be evaluated against L. infantum infection. Also, th...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Martins, Vivian Tamietti, Chávez-Fumagalli, Miguel Angel, Lage, Daniela Pagliara, Duarte, Mariana Costa, Garde, Esther, Costa, Lourena Emanuele, da Silva, Viviane Gomes, Oliveira, Jamil Silvano, de Magalhães-Soares, Danielle Ferreira, Teixeira, Santuza Maria Ribeiro, Fernandes, Ana Paula, Soto, Manuel, Tavares, Carlos Alberto Pereira, Coelho, Eduardo Antonio Ferraz
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569552/
https://ncbi.nlm.nih.gov/pubmed/26367128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137683
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