Antigenicity, Immunogenicity and Protective Efficacy of Three Proteins Expressed in the Promastigote and Amastigote Stages of Leishmania infantum against Visceral Leishmaniasis

In the present study, two Leishmania infantum hypothetical proteins present in the amastigote stage, LiHyp1 and LiHyp6, were combined with a promastigote protein, IgE-dependent histamine-releasing factor (HRF); to compose a polyproteins vaccine to be evaluated against L. infantum infection. Also, th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Martins, Vivian Tamietti, Chávez-Fumagalli, Miguel Angel, Lage, Daniela Pagliara, Duarte, Mariana Costa, Garde, Esther, Costa, Lourena Emanuele, da Silva, Viviane Gomes, Oliveira, Jamil Silvano, de Magalhães-Soares, Danielle Ferreira, Teixeira, Santuza Maria Ribeiro, Fernandes, Ana Paula, Soto, Manuel, Tavares, Carlos Alberto Pereira, Coelho, Eduardo Antonio Ferraz
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4569552/
https://ncbi.nlm.nih.gov/pubmed/26367128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137683
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