MicroRNA-135a regulates NHE9 to inhibit proliferation and migration of glioblastoma cells

BACKGROUND: Glioblastoma multiformae (GBM) is the most aggressive type of malignant brain tumor with complex molecular profile. Overexpression of Na(+)/H(+) Exchanger isoform 9 (NHE9) promotes tumor progression and correlates positively with insensitivity to radiochemotherapy and poor prognosis. How...

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Udgivet i:Cell Commun Signal
Main Authors: Gomez Zubieta, Daniela M., Hamood, Mohamed A., Beydoun, Rami, Pall, Ashley E., Kondapalli, Kalyan C.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2017
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740897/
https://ncbi.nlm.nih.gov/pubmed/29268774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-017-0209-7
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