Structure based drug discovery for designing leads for the non-toxic metabolic targets in multi drug resistant Mycobacterium tuberculosis

BACKGROUND: The problem of drug resistance and bacterial persistence in tuberculosis is a cause of global alarm. Although, the UN’s Sustainable Development Goals for 2030 has targeted a Tb free world, the treatment gap exists and only a few new drug candidates are in the pipeline. In spite of large...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Kaur, Divneet, Mathew, Shalu, Nair, Chinchu G. S., Begum, Azitha, Jainanarayan, Ashwin K., Sharma, Mukta, Brahmachari, Samir K.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740895/
https://ncbi.nlm.nih.gov/pubmed/29268770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-017-1363-9
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