Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis

The receptor-like tyrosine kinase (Ryk), a Wnt receptor, is important for cell fate determination during corticogenesis. During neuronal differentiation, the Ryk intracellular domain (ICD) is cleaved. Cleavage of Ryk and nuclear translocation of Ryk-ICD are required for neuronal differentiation. How...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Chang, Wen-Hsuan, Choi, Si Ho, Moon, Byoung-San, Cai, Mingyang, Lyu, Jungmook, Bai, Jinlun, Gao, Fan, Hajjali, Ibrahim, Zhao, Zhongfang, Campbell, Daniel B., Weiner, Leslie P., Lu, Wange
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2017
主題:
PNAS Plus
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740651/
https://ncbi.nlm.nih.gov/pubmed/29180410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1715772114
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