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Loss of APOBEC1 RNA-editing function in microglia exacerbates age-related CNS pathophysiology
Microglia (MG), a heterogeneous population of phagocytic cells, play important roles in central nervous system (CNS) homeostasis and neural plasticity. Under steady-state conditions, MG maintain homeostasis by producing antiinflammatory cytokines and neurotrophic factors, support myelin production,...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5740644/ https://ncbi.nlm.nih.gov/pubmed/29167375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710493114 |
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