Epitranscriptomic profiling across cell types reveals associations between APOBEC1-mediated RNA editing, gene expression outcomes, and cellular function

Epitranscriptomics refers to posttranscriptional alterations on an mRNA sequence that are dynamic and reproducible, and affect gene expression in a similar way to epigenetic modifications. However, the functional relevance of those modifications for the transcript, the cell, and the organism remain...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Rayon-Estrada, Violeta, Harjanto, Dewi, Hamilton, Claire E., Berchiche, Yamina A., Gantman, Emily Conn, Sakmar, Thomas P., Bulloch, Karen, Gagnidze, Khatuna, Harroch, Sheila, McEwen, Bruce S., Papavasiliou, F. Nina
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2017
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740640/
https://ncbi.nlm.nih.gov/pubmed/29167373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1714227114
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