Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection

Numerous viruses, including HIV-1, exploit the microtubule network to traffic toward the nucleus during infection. Although numerous studies have observed a role for the minus-end microtubule motor dynein in HIV-1 infection, the mechanism by which the viral core containing the viral genome associate...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Dharan, Adarsh, Opp, Silvana, Abdel-Rahim, Omar, Keceli, Sevnur Komurlu, Imam, Sabrina, Diaz-Griffero, Felipe, Campbell, Edward M.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740630/
https://ncbi.nlm.nih.gov/pubmed/29180435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712033114
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