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Bicaudal D2 facilitates the cytoplasmic trafficking and nuclear import of HIV-1 genomes during infection

Numerous viruses, including HIV-1, exploit the microtubule network to traffic toward the nucleus during infection. Although numerous studies have observed a role for the minus-end microtubule motor dynein in HIV-1 infection, the mechanism by which the viral core containing the viral genome associate...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Dharan, Adarsh, Opp, Silvana, Abdel-Rahim, Omar, Keceli, Sevnur Komurlu, Imam, Sabrina, Diaz-Griffero, Felipe, Campbell, Edward M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740630/
https://ncbi.nlm.nih.gov/pubmed/29180435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1712033114
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