Rhein lysinate protects renal function in diabetic nephropathy of KK/HlJ mice

The purpose of the present study was to assess the protective effects of rhein lysinate (RHL) in a KK/HlJ mouse model of diabetic nephropathy (DN) and to explore its mechanism of action. A total of 4 groups were established: C57BL/J control, the KK/HlJ model and 25 and 50 mg/kg/day RHL-treated KK/Hl...

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Bibliographic Details
Published in:Exp Ther Med
Main Authors: Lin, Ya-Jun, Zhen, Yong-Zhan, Wei, Jing-Bo, Wei, Jie, Dai, Jing, Gao, Jun-Ling, Li, Kai-Ji, Hu, Gang
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740561/
https://ncbi.nlm.nih.gov/pubmed/29285124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.5283
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