A Novel Animal Model for Pseudoxanthoma Elasticum: The KK/HlJ Mouse

Pseudoxanthoma elasticum is a multisystem ectopic mineralization disorder caused by mutations in the ABCC6 gene. A mouse model with targeted ablation of the corresponding gene (Abcc6(tm1JfK)) develops ectopic mineralization on the dermal sheath of vibrissae as biomarker of the progressive mineraliza...

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Detalles Bibliográficos
Autores principales: Li, Qiaoli, Berndt, Annerose, Guo, Haitao, Sundberg, John P., Uitto, Jouni
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2012
Materias:
Regular Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3463623/
https://ncbi.nlm.nih.gov/pubmed/22846719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.06.014
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