An integrated computational and experimental study uncovers FUT9 as a metabolic driver of colorectal cancer

Metabolic alterations play an important role in cancer and yet, few metabolic cancer driver genes are known. Here we perform a combined genomic and metabolic modeling analysis searching for metabolic drivers of colorectal cancer. Our analysis predicts FUT9, which catalyzes the biosynthesis of Ley gl...

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Vydáno v:Mol Syst Biol
Hlavní autoři: Auslander, Noam, Cunningham, Chelsea E, Toosi, Behzad M, McEwen, Emily J, Yizhak, Keren, Vizeacoumar, Frederick S, Parameswaran, Sreejit, Gonen, Nir, Freywald, Tanya, Bhanumathy, Kalpana K, Freywald, Andrew, Vizeacoumar, Franco J, Ruppin, Eytan
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
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Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740504/
https://ncbi.nlm.nih.gov/pubmed/29196508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20177739
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