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Smooth Muscle Cells of Human Veins Show An Increased Response to Injury at Valve Sites

OBJECTIVE: Venous valves are essential, but are prone to injury, thrombosis, and fibrosis. We compared the behavior and gene expression of smooth muscle cells (SMCs) in the valve sinus vs non-valve sites to elucidate biological differences associated with vein valves. METHODS: Tissue explants of fre...

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Detalhes bibliográficos
Publicado no:J Vasc Surg
Main Authors: Kikuchi, Shinsuke, Chen, Lihua, Xiong, Kevin, Saito, Yukihiro, Azuma, Nobuyoshi, Tang, Gale, Sobel, Michael, Wight, Thomas N, Kenagy, Richard D
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740028/
https://ncbi.nlm.nih.gov/pubmed/28647196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvs.2017.03.447
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