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Buprenorphine requires concomitant activation of NOP and MOP receptors to reduce cocaine consumption

Buprenorphine’s clinical use is approved for the treatment of heroin addiction; however, evidence supporting its efficacy in cocaine abuse also exists. While for heroin it has been demonstrated that the effect of buprenorphine is mediated by its ability to activate μ-opioid peptide receptor (MOP) re...

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Detalhes bibliográficos
Publicado no:Addict Biol
Main Authors: Kallupi, Marsida, Shen, Qianwei, de Guglielmo, Giordano, Yasuda, Dennis, Journigan, V. Blair, Zaveri, Nurulain T., Ciccocioppo, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740020/
https://ncbi.nlm.nih.gov/pubmed/28635181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/adb.12513
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