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Conformational Control of UDP-Galactopyranose Mutase Inhibition

UDP-galactopyranose mutase (Glf or UGM) catalyzes the formation of uridine 5′-diphosphate-α-D-galactofuranose (UDP-Galf) from UDP-galactopyranose (UDP-Galp). The enzyme is required for the production of Galf-containing glycans. UGM is absent in mammals, but members of the Corynebacterineae suborder...

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Bibliografski detalji
Izdano u:Biochemistry
Glavni autori: Wangkanont, Kittikhun, Winton, Valerie J., Forest, Katrina T., Kiessling, Laura L.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739916/
https://ncbi.nlm.nih.gov/pubmed/28608671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00189
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