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Antitumor effects of regorafenib and sorafenib in preclinical models of hepatocellular carcinoma

The purpose of this study was to investigate the antitumor activity of regorafenib and sorafenib in preclinical models of HCC and to assess their mechanism of action by associated changes in protein expression in a HCC-PDX mouse model. Both drugs were administered orally once daily at 10 mg/kg (rego...

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發表在:Oncotarget
Main Authors: Kissel, Maria, Berndt, Sandra, Fiebig, Lukas, Kling, Simon, Ji, Qunsheng, Gu, Qingyang, Lang, Tina, Hafner, Frank-Thorsten, Teufel, Michael, Zopf, Dieter
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739799/
https://ncbi.nlm.nih.gov/pubmed/29291014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22334
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