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Antitumor effects of regorafenib and sorafenib in preclinical models of hepatocellular carcinoma

The purpose of this study was to investigate the antitumor activity of regorafenib and sorafenib in preclinical models of HCC and to assess their mechanism of action by associated changes in protein expression in a HCC-PDX mouse model. Both drugs were administered orally once daily at 10 mg/kg (rego...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Kissel, Maria, Berndt, Sandra, Fiebig, Lukas, Kling, Simon, Ji, Qunsheng, Gu, Qingyang, Lang, Tina, Hafner, Frank-Thorsten, Teufel, Michael, Zopf, Dieter
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739799/
https://ncbi.nlm.nih.gov/pubmed/29291014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22334
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