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SPC24 promotes osteosarcoma progression by increasing EGFR/MAPK signaling
In this study, we investigated the role of the spindle checkpoint protein SPC24 in osteosarcoma progression. SPC24 knockdown in 143B and U2OS osteosarcoma cells decreased cell growth, survival and invasiveness. The SPC24 knockdown cells also exhibited low EGFR, Ras and phospho-ERK levels and high E-...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5739637/ https://ncbi.nlm.nih.gov/pubmed/29285250 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.22167 |
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