Sunitinib represses regulatory T cells to overcome immunotolerance in a murine model of hepatocellular cancer

Successful development of immunotherapeutic strategies for hepatocellular cancer (HCC) has been impeded by limited understanding of tumor-induced profound tolerance and lack of a clinically faithful HCC model. Recently, we developed a novel model that recapitulates typical features of human HCC. Usi...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Liu, Dai, Li, Guangfu, Avella, Diego M., Kimchi, Eric T., Kaifi, Jussuf T., Rubinstein, Mark P., Camp, E. Ramsay, Rockey, Don C., Schell, Todd D., Staveley-O'Carroll, Kevin F.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Editorial
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739555/
https://ncbi.nlm.nih.gov/pubmed/29296523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1372079
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