Aged interleukin-10(tm1Cgn) chronically inflamed mice have substantially reduced fat mass, metabolic rate, and adipokines

Interleukin 10(tm1Cgn) (IL 10(tm)) mice have been utilized as a model of chronic inflammation and declining health span because of their propensity to develop chronic activation in NFkB pathways, skeletal muscle and cardiac changes, and mitochondrial dysfunction. We hypothesized that older IL 10(tm)...

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Vydáno v:PLoS One
Hlavní autoři: Westbrook, Reyhan M, Yang, Huan Le, Langdon, Jackie M, Roy, Cindy N, Kim, Jin A, Choudhury, Parichoy P, Xue, Qian-Li, di Francesco, Andrea, de Cabo, Rafa, Walston, Jeremy
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739384/
https://ncbi.nlm.nih.gov/pubmed/29267271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0186811
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