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BLUNTED RESPONSE TO STRESS IN YOUNG IL-10TM/TM MICE: IMPLICATION FOR THE VULNERABILITY IN FRAILTY

The hypothalamic pituitary adrenal axis (HPA axis) is a major neuroendocrine system for stress response and for regulating the immune system. Aged rats as well as older humans demonstrate progressive loss of control of the HPA axis, resulting in impaired diurnal rhythm and hypersecretion of glucocor...

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Vydáno v:Innov Aging
Hlavní autoři: Ge, N., Yang, H., Westbrook, R., Marx-Rattner, R., Burks, T., Langdon, J., Abadir, P., Walston, J.D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243762/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.962
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