BLUNTED RESPONSE TO STRESS IN YOUNG IL-10TM/TM MICE: IMPLICATION FOR THE VULNERABILITY IN FRAILTY

The hypothalamic pituitary adrenal axis (HPA axis) is a major neuroendocrine system for stress response and for regulating the immune system. Aged rats as well as older humans demonstrate progressive loss of control of the HPA axis, resulting in impaired diurnal rhythm and hypersecretion of glucocor...

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發表在:Innov Aging
Main Authors: Ge, N., Yang, H., Westbrook, R., Marx-Rattner, R., Burks, T., Langdon, J., Abadir, P., Walston, J.D.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6243762/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igx004.962
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