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New chemical and radiochemical routes to [(18)F]Rho6G-DEG-F, a delocalized lipophilic cation for myocardial perfusion imaging with PET

New chemical and radiochemical syntheses are described for the preparation of [(18)F]Rho6G-DEG-F, an (18)F-labeled analogue of the fluorescent dye rhodamine 6G, which has shown promise as myocardidal perfusion imaging agent. Tosylated precursors of [(18)F]Rho6G-DEG-F amenable to (18)F-labeling were...

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Detalhes bibliográficos
Publicado no:Medchemcomm
Main Authors: Inkster, J. A. H., Zhang, S., Akurathi, V., Belanger, A., Dubey, S., Treves, S. T., Packard, A. B.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5739059/
https://ncbi.nlm.nih.gov/pubmed/29276578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00326a
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