The contribution of the TP53 R337H mutation to the cancer burden in Southern Brazil: Insights from the study of 55 families of children with adrenocortical tumors

BACKGROUND: The TP53 R337H mutation predisposes children to adrenocortical tumors (ACT) and, rarely, to other childhood tumors, but its impact on adult cancer remains undetermined. This study investigated the frequency and types of cancer in relatives of children with ACT who carry the TP53 R337H mu...

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Détails bibliographiques
Publié dans:Cancer
Auteurs principaux: Mastellaro, Maria J., Seidinger, Ana L., Kang, Guolian, Abrahão, Renata, Miranda, Eliana C. M., Pounds, Stanley, Cardinalli, Izilda A., Aguiar, Simone S., Figueiredo, Bonald C., Rodriguez-Galindo, Carlos, Brandalise, Silvia R., Yunes, José A., Barros-Filho, Antônio de A., Ribeiro, Raul C.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738920/
https://ncbi.nlm.nih.gov/pubmed/28387921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30703
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