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TP53 p.Arg337His geographic distribution correlates with adrenocortical tumor occurrence

BACKGROUND: The p.Arg337His mutation of the TP53 is the most frequent germline missense variant associated with cancer described so far in this gene. It is mainly found in the South and Southeastern regions of Brazil, where it has been associated with a high incidence of pediatric adrenocortical (AC...

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Bibliografske podrobnosti
izdano v:Mol Genet Genomic Med
Main Authors: Seidinger, Ana L., Caminha, Isabel P., Mastellaro, Maria J., Gabetta, Carmen S., Nowill, Alexandre E., Pinheiro, Vitória R. P., Yunes, José A.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503091/
https://ncbi.nlm.nih.gov/pubmed/32592449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.1168
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