Mutation and Suppressor Analysis of the Essential Lipopolysaccharide Transport Protein LptA Reveals Strategies To Overcome Severe Outer Membrane Permeability Defects in Escherichia coli

In Gram-negative bacteria, lipopolysaccharide (LPS) contributes to the robust permeability barrier of the outer membrane (OM), preventing the entry of toxic molecules, such as detergents and antibiotics. LPS is transported from the inner membrane (IM) to the OM by the Lpt multiprotein machinery. Def...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Falchi, Federica A., Maccagni, Elisa A., Puccio, Simone, Peano, Clelia, De Castro, Cristina, Palmigiano, Angelo, Garozzo, Domenico, Martorana, Alessandra M., Polissi, Alessandra, Dehò, Gianni, Sperandeo, Paola
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738735/
https://ncbi.nlm.nih.gov/pubmed/29109183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00487-17
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