Thanatin Impairs Lipopolysaccharide Transport Complex Assembly by Targeting LptC–LptA Interaction and Decreasing LptA Stability

The outer membrane (OM) of Gram-negative bacteria is a highly selective permeability barrier due to its asymmetric structure with lipopolysaccharide (LPS) in the outer leaflet. In Escherichia coli, LPS is transported to the cell surface by the LPS transport (Lpt) system composed of seven essential p...

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Detalles Bibliográficos
Publicado en:Front Microbiol
Main Authors: Moura, Elisabete C. C. M., Baeta, Tiago, Romanelli, Alessandra, Laguri, Cedric, Martorana, Alessandra M., Erba, Emanuela, Simorre, Jean-Pierre, Sperandeo, Paola, Polissi, Alessandra
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2020
Assuntos:
Microbiology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7237710/
https://ncbi.nlm.nih.gov/pubmed/32477309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2020.00909
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