Nicotine Prevents and Reverses Paclitaxel-Induced Mechanical Allodynia in a Mouse Model of CIPN

Chemotherapy-induced peripheral neuropathy (CIPN), a consequence of peripheral nerve fiber dysfunction or degeneration, continues to be a dose-limiting and debilitating side effect during and/or after cancer chemotherapy. Paclitaxel, a taxane commonly used to treat breast, lung, and ovarian cancers,...

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Bibliographic Details
Published in:J Pharmacol Exp Ther
Main Authors: Kyte, S. Lauren, Toma, Wisam, Bagdas, Deniz, Meade, Julie A., Schurman, Lesley D., Lichtman, Aron H., Chen, Zhi-Jian, Del Fabbro, Egidio, Fang, Xianjun, Bigbee, John W., Damaj, M. Imad, Gewirtz, David A.
Format: Artigo
Language:Inglês
Published: The American Society for Pharmacology and Experimental Therapeutics 2018
Subjects:
Chemotherapy, Antibiotics, and Gene Therapy
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738719/
https://ncbi.nlm.nih.gov/pubmed/29042416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.243972
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