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A polyclonal origin of parathyroid tumors is common and is associated with multiple gland disease in primary hyperparathyroidism

BACKGROUND: Parathyroid tumors are mostly considered monoclonal neoplasms, the rationale for focused parathyroidectomy (PTX) in primary hyperparathyroidism (PHPT). We reported that flow sorting parathyroid tumor cells and methylation-sensitive PCR (me-PCR) of polymorphic HUMARA and PGK alleles in DN...

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Vydáno v:Surgery
Hlavní autoři: Shi, Yuhong, Azimzadeh, Pedram, Jamingal, Sarada, Wentworth, Shannon, Ferlitch, Janice, Koh, James, Balenga, Nariman, Olson, John A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738672/
https://ncbi.nlm.nih.gov/pubmed/29254595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2017.04.038
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