Semaphorin 4D inhibits neutrophil activation and is involved in the pathogenesis of neutrophil-mediated autoimmune vasculitis

OBJECTIVES: Inappropriate activation of neutrophils plays a pathological role in antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). The aim of this study was to investigate the functions of semaphorin 4D (SEMA4D) in regulation of neutrophil activation, and its involvement in AAV...

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Udgivet i:Ann Rheum Dis
Main Authors: Nishide, Masayuki, Nojima, Satoshi, Ito, Daisuke, Takamatsu, Hyota, Koyama, Shohei, Kang, Sujin, Kimura, Tetsuya, Morimoto, Keiko, Hosokawa, Takashi, Hayama, Yoshitomo, Kinehara, Yuhei, Kato, Yasuhiro, Nakatani, Takeshi, Nakanishi, Yoshimitsu, Tsuda, Takeshi, Park, Jeong Hoon, Hirano, Toru, Shima, Yoshihito, Narazaki, Masashi, Morii, Eiichi, Kumanogoh, Atsushi
Format: Artigo
Sprog:Inglês
Udgivet: Annals of the Rheumatic Diseases 2017
Fag:
Basic and Translational Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738596/
https://ncbi.nlm.nih.gov/pubmed/28416516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2016-210706
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