Novel role for endogenous mitochondrial formylated peptide-driven formyl peptide receptor 1 signalling in acute respiratory distress syndrome

BACKGROUND: Acute respiratory distress syndrome (ARDS) is an often fatal neutrophil-dominant lung disease. Although influenced by multiple proinflammatory mediators, identification of suitable therapeutic candidates remains elusive. We aimed to delineate the presence of mitochondrial formylated pept...

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Detalhes bibliográficos
Publicado no:Thorax
Main Authors: Dorward, David A, Lucas, Christopher D, Doherty, Mary K, Chapman, Gavin B, Scholefield, Emma J, Conway Morris, Andrew, Felton, Jennifer M, Kipari, Tiina, Humphries, Duncan C, Robb, Calum T, Simpson, A John, Whitfield, Phillip D, Haslett, Christopher, Dhaliwal, Kevin, Rossi, Adriano G
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Respiratory Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738532/
https://ncbi.nlm.nih.gov/pubmed/28469031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/thoraxjnl-2017-210030
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